Innocent Bystander or A Culprit Causal Role of Uric Acid on The Risk of Metabolic Syndrome

Innocent Bystander or A Culprit? Causal Role of Uric Acid on Metabolic Syndrome

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Researchers found that uric acid increment may augment the risk of metabolic syndrome through increasing blood pressure and triglyceride levels and lowering HDL-C value but not through accumulating fat or hyperglycemia.
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Bacteria - The Original Origin Story with Dr. Chih-Horng Kuo

Bacteria – The Original Origin Story with Dr. Chih-Horng Kuo

Dr. Chih-Horng Kuo, Research Fellow from the Institute of Plant and Microbial Biology in Academia Sinica answers these questions and illustrates how studying the history of bacterial evolution is important for our future

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The Conundrum of Climate Change - Dr. Pao Kuan Wang

The Conundrum of Climate Change – Dr. Pao Kuan Wang

Dr. Pao Kuan Wang, Director and Distinguished Research Fellow from the Research Center for Environmental Changes at Academia Sinica tackles the ever-important Climate change debate

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Is CryoEM the Future of Cell Biology

Is CryoEM the Future of Cell Biology?

In this episode, Dr. Ming Daw Tsai and Dr. Yi-Ming Wu from Academia Sinica CryoEM Center discusses the principle, methodology, advantages, and future of CryoEM

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Gravity of the Blackhole Image - Dr.Kevin Koay and Dr.Shoko Koyama

Gravity of the Blackhole Image – Dr.Kevin Koay and Dr.Shoko Koyama

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What is a black hole? Why could we not image it before? Why is the recent blackhole image important? Is it one of the keys to unraveling the universe? What questions does it answer and inspire? All this and more with Dr.Kevin Koay and Dr.Shoko Koyama on STEMSpeak Podcast
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Economics of Agriculture and Climate Change - Dr. Emily Chang

Economics of Agriculture and Climate Change – Dr. Emily Chang

Dr. Emily Chang from The Institute of Economics, Academia Sinica talks about how agricultural policies are designed based on production efficiency, demand, and supply chains, what are the challenges in measuring climate change and developing sustainable economic policies

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Evolution of Genes, Genomes and Technology

Evolution of Genes, Genomes and Technology – Dr. Wen-Hsiung Li

Dr. Wen-Hsiung Li from the Biodiversity Research Center in Academia Sinica talks about how comparing the genetic codes of different species helps us understand their evolutionary origins and how this fundamental knowledge can be translated into producing important enzymes and hormones

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The Calcium and Cardiac connect - Dr. Chien-Chang Chen

The Calcium and Cardiac connect – Dr. Chien-Chang Chen

Dr. Chien-Chang Chen from the Institute of Biomedical Sciences in Academia Sinica talks about how calcium in our heart cells is important for cardiac structure and function

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Careers Beyond Academia – With Dr. Kevin Tsai

Careers Beyond Academia – With Dr. Kevin Tsai

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In this segment of STEMSpeak, we talk to Ph.D. graduates who have carved a career in industry. Our first featured guest is Dr. Kevin Tsai
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Linguistics is the chemistry of language

Evolution of Language – With Dr. Jonathan Evans

In this edition of STEM101, we dissect the role of technology and communication in the evolution of language with Dr. Jonathan Evans. Dr. Evans from the Institute of Linguistics is an expert on historical phonology and phonetics

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What can we understand about neural circuits from the Drosophila visual system

What can we understand about neural circuits from the Drosophila visual system?

Dr. Chi-Hon Lee, the director of the Institute of Cellular and Organismic Biology at Academia Sinica, answers many questions like why Drosophila is a good animal model to study the nervous system

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Dr. Tien Hsien Chang On How He Became a Scientist – Part 2

Dr. Tien Hsien Chang On How He Became a Scientist – Part 2

Those who know Dr. Chang, know that he teaches an exciting course titled ‘To be a scientist’, where we trace the life and times of some of the greatest scientists of the 21st century. Here, he talks about his journey as a scientist.

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Dr. Tien Hsien Chang On How He Became a Scientist – Part 2

Dr. Tien Hsien Chang On How He Became a Scientist – Part 1

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Those who know Dr. Chang, know that he teaches an exciting course titled ‘To be a scientist’, where we trace the life and times of some of the greatest scientists of the 21st century. Here, he talks about his journey as a scientist.
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Astronomers witness galaxy megamerger

Astronomers Have Witnessed the Beginnings of A Gargantuan Cosmic Pileup

Peering deep into space -- an astounding 90 percent of the way across the observable universe -- astronomers have witnessed the beginnings of a gargantuan cosmic pileup, the impending collision of 14 young, starbursting galaxies.

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CircRNA – A Key to Unlocking Pluripotent Stem Cells for Regenerative Medicine or Other Innovative Medical Technologies

When cells in the human body become aged or injured, pluripotent stem cells may provide a means for repair. These cells can be induced to form a variety of different cell types and may be able to replace dysfunctional cells or regrow damaged tissues.

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A Glycan That Completes the Journey of B cell

By altering the intracellular protein modification with sugar, Dr. Kuo-I Lin’s lab made B cells in mice turn lethargic when they reach a mature age and mount the antibody responses.

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Extralchromosomal telomere repeat DNA activates cytosolic DNA sensing pathway and influences ALT development

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A recent study at the Institute of Molecular Biology, Academia Sinica discovers that extra-chromosomal telomere repeat (ECTR) DNA molecules can activate cytosolic DNA sensing pathways that may inhibit alternative lengthening of telomeres (ALT) cancer development.
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Metro Rail System Cause the Artificial Magnetic Disturbance

An obvious magnetic disturbance has been repeatedly observed by magnetometers located outside of urban areas in Yangmingshan National Park and has affected the monitoring of volcanic activity in the northern region of Taiwan.

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A green light for green chemistry: the discovery of new enzymes synthesizing alkaloid natural products

 In nature, living organisms use primary metabolites containing simple building blocks as their starting materials. An important part of utilizing these starting materials is enzymes, which efficiently catalyze a variety of chemical reactions and generate a large number of natural products through biosynthetic pathways.

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7th Asian Symposium on Plant Lipid-ASPL2017

Academia Sinica is organizing 7th Asian Symposium on Plant Lipid (ASPL2017). This event will be held at Academia Sinica campus, Taipei, Taiwan from 29th November to 2nd of December 2017. 

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2017 International Conference of Developmental Biology, Stem Cells and Regenerative Medicine – from Basic Research to Applications

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2017 International Conference of Developmental Biology, Stem Cells and Regenerative Medicine - from Basic Research to Applications
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Complex Organic Molecules Found on “Space Hamburger” — Prebiotic Atmosphere Discovered on Accretion Disk of Baby Star

An international research team, led by Chin-Fei Lee of the Academia Sinica Institute of Astronomy and Astrophysics (ASIAA, Taiwan), has used the Atacama Large Millimeter/submillimeter Array (ALMA) to detect complex organic molecules for the first time in the atmosphere of an accretion disk around a very young protostar.

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Interview with Dr. Rita P.Y. Chen, Associate Research Fellow at Academia Sinica

Dr. Rita Chen is an Associate Research Fellow at the Institute of Biological Chemistry (IBC) and is also a TIGP-CBMB faculty member. Dr. Chen was awarded her Ph.D. degree from the Department of Biochemistry at the prestigious University of Cambridge in 1998.

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Drug Capture System Developed to treat Limb Ischemia

Dr. Patrick Ching-Ho Hsieh, Dr. Steve Roffler, and colleagues at the Institute of Biomedical Sciences have announced a new treatment for limb ischemia that may solve many of the traditional problems for treating the disease.

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Targeting BDNF in the medial thalamus for the treatment of central poststroke pain in a rodent model

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Approximately 7-10% of patients develop a chronic pain syndrome after the stroke. This chronic pain condition is called central poststroke pain (CPSP).
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Antibody targeting IL-17B/RB proved effective for pancreatic cancer

Of all battles against cancer, when it comes to the therapeutics for pancreatic cancer, more than ever, it is too little and too late. That is why, when Dr. Wen-Hwa Lee’s team developed an antibody and proved that it can extend the life of lab mice to twice longer than its compared group, the participating scientists are excited, for they have pushed the milestone one step further in finding the therapeutics for pancreatic cancer patients

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Peptide Nasal Spray to Delay Onset of Alzheimer’s disease

Dr. Rita P.-Y. Chen, an Associate Research Fellow at the Institute of Biological Chemistry along with Dr. Pang-hsien Tu, a former Assistant Research Fellow at the Institute of Biomedical Sciences, and their research teams recently found that a modified short peptide delays the onset of Alzheimer’s disease when delivered in the form of a nasal drop in a mouse model.

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Research Integrity and Publishing Ethics Workshop Was Held At Academia Sinica, Taiwan

Research misconduct is increasingly a problem in the Taiwan academic community and recently has become an important issue. Society expects ethical behavior to come naturally for a researcher at our national academic institutions.

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An Extraordinary Celestial Spiral with a Twist–ALMA adds a new dimension to a Hubble Space Telescope result

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An international team of astronomers, led by Dr. Hyosun Kim in Academia Sinica Institute of Astronomy and Astrophysics (ASIAA, Taiwan), has found a way of deriving the orbital shape of binary stars that have orbital periods too long to be directly measured.
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Interview with Dr. Kevin Tsai, Alumni of Academia Sinica, Taiwan

Kevin Tsai recently graduated from the Ph.D. program in Bioinformatics at Academia Sinica, Taiwan. Prior to graduating, he did contract work with McKinsey & Co. and held positions at Gilead Sciences and Celera.

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The protein responsible for the accumulation of somatic mutations in multiple cancers is identified.

Researchers from Taiwan identify the protein responsible for the accumulation of somatic mutations in various cancers. The study conducted by Dr. Shen, Chen-Yang and his team at Institute of Biomedical Sciences, Academia Sinica, shows that the protein B-Myb–A3B contributes to DNA damage and could be targeted by inhibiting Epidermal Growth Factor receptor (EGFR).   One […]

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